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Russia says it developed COVID-19 treatment based on anti-malaria drug

Russia’s Federal Biomedical Agency on Saturday said it has developed a drug for the treatment of COVID-19. The agency said its drug was based on mefloquine, which is used to prevent or treat malaria. The drug will allegedly provide effective treatment for COVID-19 patients with varying severity. The agency said it was developing an effective

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Oxycodone-with-naloxone controlled-release tablets (Targin) for chronic severe pain

An option for people with opioid-induced constipation Key points Provides equivalent analgesia to that of oxycodone controlled-release (CR) tabletsClinical data are largely from people with chronic musculoskeletal pain. The naloxone component reduces, but does not eliminate, opioid-induced constipationIn key trials, the prevalence of constipation with oxycodone-with-naloxone CR compared with oxycodone CR was about 25% lower